Jaundice is commonly caused by conditions such as pancreatic cancer, which causes blockage of the bile duct passing through the cancerous portion of the pancreas; cholangiocarcinoma, cancer of the bile ducts; blockage by a stone in patients with gallstones; and from scarring after injury to the bile duct during gallbladder removal.
When Harvey heads to Monte Carlo on vacation, a pill in his drink at the Casino causes severe abdominal pain which is made to look like a Gallstone, and Adrian operates, though barely breaking the skin, and collects a large bill.