Genetic admixture, the result of interbreeding between two or more previously isolated populations within a species.
About 100,000 years ago, some H. sapiens sapiens migrated from Africa to the Levant and met with resident Neanderthals, with some admixture.
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However, this does not negate a possible Medieval Jewish origin for some of the Pashtun sub-tribes, but this would depend on the frequency of G2b among the Pashtuns, since any Jewish genetic admixture in relatively recent times would have been limited in scope.