In 1629, Viceroy Diego Fernández de Córdoba gave up his charge and returned to Spain, where he died the following year, at Guadalcázar, aged 52.
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In 1598, aged 20, he was in Central Europe as an ambassador with a mandate to travel and bring back to Spain the 13-14 year old orphaned bride Margaret of Austria (daughter of Archduke Charles II of Austria and Maria Anna of Bavaria), the first, and unique, wife of king Philip III of Spain, being awarded the title of marquis of Guadalcázar, in 1609.