Nashe if referring to the exotic medicinal plant Guaiacum, the name of which was also "exotic", being the first Native American word imported into the English language.
The term guaiac denotes the name of the paper surface used in the test which has a phenolic compound, alpha-guaiaconic acid, that is extracted from the wood resin of Guaiacum trees.
Gaukes also popularized Species Lignorum, a variant of the numerous Guaiacum wood extracts that had been used to treat syphilis since the late 16th century.
Lignum vitae, heartwood of tree species of the genus Guaiacum, native to subtropical and tropical regions of the Americas