After two major slave raiding attacks in 1680, the Santa Catalina de Guale mission was moved south to Sapelo Island.
•
In 1684 the Santa Catalina de Guale mission was moved to Amelia Island in present-day Florida.
Franciscan brothers were missionaries to the Timucua and Guale Indians along the coast, whose territory included the Sea Islands in Georgia and up to the Savannah River.