At the same time, it promotes dissociation of any bound GDP from the protein, enhancing GTP binding.
Microtubules are essential to cell division, and taxanes stabilize GDP-bound tubulin in the microtubule, thereby inhibiting the process of cell division — a "frozen mitosis".
Guanosine triphosphate | Guanosine diphosphate | Cyclic guanosine monophosphate | Uridine diphosphate | Adenosine diphosphate | Uridine diphosphate galactose | cyclic guanosine monophosphate |