In 2006, he joined a rookie cast that included Hanley Ramírez, Dan Uggla, Jeremy Hermida, Josh Johnson, Josh Willingham, Eric Reed, Mike Jacobs, and Scott Olsen, a group that overperformed considering the meager expectations, which were placed on them due to the frugal nature of Marlins owner Jeffrey Loria.
Hanley | Hanley, Staffordshire | Framing Hanley | Richard Ramirez | Édgar Ramírez | Raúl Ramírez | Kay Hanley | Hanley Ramírez | Danny Perez Ramírez | Ariel Ramírez | William Edward Hanley Stanner | Héctor Fernando Ramírez | Eugene Hanley | Ellery Hanley | Ram Ramirez | Michael Ramirez | Jeremy Hanley | Hanley Castle | Efren Ramirez | Dania Ramirez | Carlos Ramirez | Ben Hanley | Alec Hanley Bemis | Yola Ramírez | Yessica Ramírez | Victor R. Ramirez | Victoria Hall (Hanley) | Saul N. Ramirez, Jr. | Richard Hanley | Pedro J. Ramírez |
Besides Wakefield and Youkilis, other Major League Baseball players that performed at Lake Olmstead Stadium include Moisés Alou, Emmanuel Burriss, Carlos García, Brian Horwitz, Jason Kendall, Orlando Merced, Hanley Ramírez, Brandon Moss, Luis Mendoza, Pablo Sandoval, Eugenio Vélez Brian Wilson, Madison Bumgarner and Tony Womack.
The Marlins traded him to Boston in a deal that was officially completed on November 21, 2005, in which the Red Sox received Lowell, Josh Beckett and Guillermo Mota in exchange for Hanley Ramírez, Aníbal Sánchez, Jesús Delgado and Harvey García.