Players on the Physically Unable to Perform (PUP) list may not practice, but do count towards the team's 53-man roster limit.
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The medical costs for catastrophic injuries can be extremely high—a 2011 estimate from the Mational Spinal Cord Injury Statistical Center notes that first-year costs of someone who has high tetraplegia, an injury that causes partial or full loss of use in all limbs, is USD $1,044,097, with subsequent years costing $181,328.
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NFL commissioner Roger Goodell addressed the issue of head injuries in professional football during a talk held on November 15, 2012 at the Harvard School of Public Health.
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