Heffer Wolfe, character from the Nicktoon Rocko's Modern Life
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Heather Trott, character from the BBC soap Eastenders (nicknamed "Heffer" by Gary Bushell)
Jeff "Swampy" Marsh, a storyboard writer, says that Heffer's right eye and left nostril are "notched at the bottom" due to Murray's design style.
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It is revealed in an episode (Specifically the episode 'Who's for Dinner?', where Heffer's "birthmark" is also revealed) that Heffer's biological father is still alive with a girl cow named Joyce living in a trailer in the Canoga Park section of the San Fernando Valley region of Los Angeles, California, United States.