In 1796 three sections of a tessellated Roman mosaic pavement depicting Greek mythological figures were discovered by workmen in the grounds of Horkstow Hall.
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In 1756 artist George Stubbs stayed at Manor Farmhouse to pursue analytical examination and meticulous drawing of horse carcasses acquired from nearby tanneries.
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Charles Gore was born at Horkstow Hall in 1729, he married well and died at Weimar in German high society.
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Historic folk associations with the Grange inspired the Steeleye Span band name, and their album Horkstow Grange.
He was responsible for the New River Ancholme Drainage Scheme in Lincolnshire, and Horkstow Bridge, which he designed to cross the river at Horkstow in 1835–6, is one of the earliest suspension bridges to survive and remains substantially as designed.