Various periods of struggle and domination by the Visconti followed until, in 1447, Castano came under the control of the House of Sforza who gave it as fiefdom to a family favourite.
The commune of Pavia defeated the Counts in the 1140s and captured Lomello, owning it until 1360, when Lomello underwent the domination of the Visconti, who were followed, from 1450 to 1535, by the Sforza.
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When the Visconti family died out in the 15th century, the emblem retained its association with the Duchy of Milan and became part of the coats of arms of the House of Sforza; the presence of Biscione in Poland (Sanok) and Belarus (Pruzhany) is due to queen Bona Sforza.
These qualities made the Castellanza a strategic base for the House of Visconti and the House of Sforza of the Duchy of Milan until the Battle of Novara (1513).