X-Nico

3 unusual facts about IPI-926


IPI-926

Depending on when a Hh inhibiting compound is approved by the U.S. Food and Drug Administration (FDA), there may be a perceived need for one to be differentiated over another for marketing purposes, which could lead to different nomenclature (e.g., a Hhi or an agonist of Smo).

The process begins with cyclopamine extracted from harvested Veratrum californicum which is taken through a series of alterations resulting in an analogue of the natural product cyclopamine, making IPI-926 the only compound in development/testing that is not fully synthetic.

Veratrum californicum

One derivative of it, compound name IPI-926, is currently undergoing clinical trials for the treatment of various types of cancer, including hard-to-treat hematologic malignancies, chondrosarcoma, and pancreatic cancer.


Similar

Ipi Tombi | IPI-926 |

Arizona Green Party

Prominent Green candidates in Arizona have included Vance Hansen, who ran for the US Senate in 2000 and received 108,926 votes, Claudia Ellquist who ran for Pima County Attorney in 2004 on a platform largely focused on declaring a moratorium on the death penalty, and Dave Croteau who ran for mayor of Tucson in 2007 on a platform of relocalization and received over 28% of the vote.

Cardinia Transit

926 PakenhamWestfield Fountain Gate via Lakeside, Beaconsfield station & Berwick (Daily)

Consort Xu

Empress Dowager Xu (died 926), known as Consort Xu (徐賢妃) of the Former Shu before she became empress dowager

Faqir of Ipi

He moved to Ipi in mid 1920s and later went to perform Hajj at Mecca.

Hold On, I'm Comin'

Stax Records was an old Movie Theater located at 926 East McLemore Avenue in Memphis, Tennessee.

Intelligent Peripheral Interface

IPI systems were often shipped by Sun Microsystems on original sun4 architecture servers, but the above limitation and reliability problems made them unpopular with customers, and the technology basically disappeared by the second half of the 1990s.

International Peace Institute

Since 2005, IPI has been led by Terje Rød-Larsen, a principal architect of the Oslo Peace Accords (between the PLO and the Government of Israel) and a Norwegian sociologist and diplomat who has served the UN as its senior envoy in the Middle East.

Ipi Tombi

Ipi Tombi (also produced as Ipi N'tombi, both corrupted transliterations of the Zulu iphi intombi, or "where is the girl?"), is a 1974 musical by South African writers Bertha Egnos Godfrey and her daughter Gail Lakier, telling the story of a young black man leaving his village and young wife to work in the mines of Johannesburg.

James L. Gulley

This phase I trial using PSA-TRICOM with Ipilimumab (Ipi) showed promise for Overall Survival (OS).

Laneshaw Bridge

It has been claimed that this the Eamot where in AD 926 King Athelstan, confirmed a treaty of peace between the Welsh, Scots and Northumbrians.

Main–Spessart railway

The Schwarzkopf Tunnel (926 m long), located between Laufach and Heigenbrücken will be replaced with four new tunnels which will allow for faster operations.

Matome Ugaki

The next morning, the crew of American landing craft LST-926 found the still smoldering remains of a cockpit with three bodies on the beach of Ishikawajima.

Pedro Joaquín Chamorro Cardenal

Speaking about her husband to the participants of the 1998 IPI World Congress in Moscow, Violeta said: “During his whole life, Pedro Joaquín Chamorro was a tireless fighter for democracy in Nicaragua and against the dictatorship of Somoza. This cost him incarceration, torture, exile and finally death. He was warned many times that plans existed to assassinate him, yet no threat detained him from fulfilling his mission to impart the truth and preach democracy.”

R. Kent Hughes

Preach The Word: Essays on Expository Preaching In Honor of R. Kent Hughes (ISBN 1-58134-926-2) included contributions by David Jackman, D. A. Carson, Wayne Grudem, John F. MacArthur, Bruce Winter, J. I. Packer, Phillip Jensen, Philip Graham Ryken, and Peter Jensen.

Råpi

Råpi (also, Ropi) is a 926 meters high mountain in Norrbotten County, northern Sweden, near Kiruna.

St German's Priory

The church is dedicated to St Germanus and soon after construction it became the cathedral for Cornwall in 926 AD, when King Athelstan appointed Conan as the bishop of Cornwall.

Zhang Yan

Zhang Quanyi (張全義; 852-926), also known as Zhang Yan (張言), late Tang Dynasty / Five Dynasties warlord


see also