Igé, Orne, a commune in the French region of Basse-Normandie
The first was Jules Trottier, born around 1591 in Igé (Orne, Normandy, France), dispatched to New France by contract at La Rochelle on July 4, 1646.
In molecular biology, the CD20-like family of proteins includes the CD20 protein and the beta subunit of the high affinity receptor for IgE Fc, MS4A2.
Tanox, a biotech company based in Houston, Texas, proposed in 1987 that by targeting membrane-bound IgE (mIgE) on B lymphoblast and memory B cells, those cells can be lysed or down-regulated, thus achieving the inhibition of the production of antigen-specific IgE and hence a shift of immune balance toward non-IgE mechanisms.
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IgE is known to be elevated in various autoimmune disorders such as Lupus(SLE), Rheumatoid Arthritis(RA) & psoriasis, and is theorized to be of pathogenetic importance in RA and SLE by eliciting a hypersensitivity reaction.
Media reports claim that Collins-Rector was a silent partner in the MMORPG service company IGE, which was founded by ex-DEN VP Brock Pierce.