Owing to the Schmalkaldic War in Germany he was compelled to seek asylum in England, where he resided at Lambeth Palace with Archbishop Cranmer in 1547.
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Guy probably kept company with a number of refugees from continental Europe: Tremellius, Valérand Poullain, Martin Bucer, John a Lasco, Jan Utenhove, Marten de Klyne (Marten Micron or Micronius), Wouter Deelen, François Perucel de la Rivière and others.