IgG also plays an important role in antibody-dependent cell-mediated cytotoxicity (ADCC) and intracellular antibody-mediated proteolysis, in which it binds to TRIM21 (the receptor with greatest affinity to IgG in humans) in order to direct marked virions to the proteasome in the cytosol.
Intravenous immunoglobulin | intravenous immunoglobulin | Immunoglobulin Y | Immunoglobulin light chain | Immunoglobulin heavy chain | Immunoglobulin D |