Illinois | University of Illinois at Urbana-Champaign | Interstate 75 | Peoria, Illinois | Interstate 90 | Rockford, Illinois | Evanston, Illinois | Springfield, Illinois | Interstate 5 | Northern Illinois University | Interstate 94 | Cook County, Illinois | Interstate 81 | Interstate 80 | Interstate 70 | Interstate 40 | Illinois Institute of Technology | Interstate 95 | Interstate 10 | Joliet, Illinois | Interstate 65 | Interstate 64 | Interstate 44 | Interstate 90 in Minnesota | Rock Island, Illinois | Interstate 71 | Interstate 35 | Belleville, Illinois | Aurora, Illinois | Southern Illinois University |
Running parallel to the Indiana border, it is also the longest state road, starting on the south side of Chicago as Halsted Street at an interchange with Interstate 57 (I–57), south to a free ferry crossing to Kentucky at Cave-in-Rock on the Ohio River.