During his military service he injured his back, displacing a disc.
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These tests reveal any degenerative changes and determine the details of each nerve, bone, and discs, and they are done through MRI’s, X-rays, and CT scans.
A disc protrusion is a disease condition which can occur in some vertebrates, including humans, in which the outermost layers of the annulus fibrosus of the intervertebral discs of the spine are intact, but bulge when one or more of the discs are under pressure.
Tobinick has been issued patents for methods of perispinal administration, of certain recombinant DNA-derived (biologic) therapeutics including the TNF receptor fusion protein etanercept, for the treatment of certain neurologic disorders with widespread unmet medical need, including Alzheimer's disease; pain due to cancer metastasis to bone; severe, intractable, intervertebral disc-related pain and radiculopathy (including sciatica); and myasthenia gravis.
Thrombospondins, intervertebral disc proteins, regulate the effective levels of matrix metalloproteinases (MMPs) 2 and 9, which are key effectors of ECM remodeling.
Ventral slot surgery is used in dogs to decompress the cervical spine after an intervertebral disc extrusion(being forced or pressed out).