The Angel Island Speckled Rattlesnake (Crotalus angelensis) and Angel Island mouse (Peromyscus guardia) occur only on the island.
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Also, the islands of Baja California located in the Gulf of California are part of the municipality, among them the mudflat islands at the mouth of the Colorado River (the largest one being Montague Island), Isla Ángel de la Guarda and the islands of the San Lorenzo Marine Archipelago National Park.
His travels included journeys to the peninsula's west coast, to Isla Angel de la Guarda, and to the north in an ambitious but failed attempt to reach the lower Colorado River and settle once and for all the geographical question of whether Baja California was an island.