Lamine entered government as a representative of the eastern town of N'Gourti in 2000.
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Following the 1999 coup and return to civilian rule, Lamine became political leader from his base in N'Gourti, and from 5 January 2000 served as Minister in a series of governments.
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Following the January 2011 parliamentary election, Issa was accused by local military governors in N'Gourti and Diffa Region of attempting to fix the elections in N'Gourti by orchestrating the kidnap of election officials, and organizing groups of his CDS-Rahama supporters and ex-combatants from his 1990s rebel group to attack areas presumed loyal to rivals.
Issa | Kobayashi Issa | Darrell Issa | Issa J. Boullata | Issa Hayatou | Serigne Mouhamadou Lamine Bara Mbacké | Mohamed Lamine Sanha | Mohamed Lamine | Mohamed Bin Issa Al Jaber | Mahmoud Mohammad Issa Mohammad | Mahmadu Lamine | Lamine Diack | Issa Serge Coelo | Issa Boulos |