When Maxtla laid siege to Tenochtitlan in 1428, Chimalpopoca's successor and uncle, Itzcoatl, repelled his forces with the aid of an alliance of city states, including Texcoco under Nezahualcoyotl and many former Tepanec allies, notably Tlacopan.
The station and its surrounding area have this name because of nearby monuments to two Aztec emperors, Itzcoatl and Ahuizotl.