A Jacobite sympathiser, he is best known for his defence of rebels standing trial at Carlisle after the Jacobite risings.
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Bonnie Dundee is the of title of a poem and a song written by Walter Scott in 1825 in honour of John Graham, 7th Laird of Claverhouse, who was created 1st Viscount Dundee in November 1688, then in 1689 led a Jacobite rising in which he died, becoming a Jacobite hero.
His successor was his son William, who joined the Jacobite standard at Braemar, during the rising of 1715, and then, having raised 3000 men, was present at the battle of Sheriffmuir and was appointed lieutenant-general of the northern counties.
The restoration of Charles II was not without incident, and with the Act of Settlement came the Jacobite Risings, to which Perth was supportive.
In 1715, James II's son James Francis Edward Stuart, also known as the Old Pretender attempted to regain the throne by launching a Jacobite Rising in Scotland.
Leake himself lived in Mile End, where he was active in vestry affairs and helped raise volunteer units during the Jacobite rising of 1745, and at Thorpe-le-Soken in Essex, where his father had acquired an estate in 1720.
The de jure third Baronet was physician to Bonnie Prince Charlie during the Jacobite rising of 1745 and President of the Royal Medical Society from 1766 to 1770.