Mann began his career in the laboratory of Professor Jacob Karol Parnas (1884-1949) in Poland, where he was involved in research on glycolysis and muscle energy metabolism.
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The discovery of the Embden–Meyerhof–Parnas pathway by Gustav Embden, Otto Fritz Meyerhof and Jakub Karol Parnas in the early 20th century contributed more to the understanding of the complex chemical processes involved in the conversion of sugar to alcohol.
The most common type of glycolysis is the Embden–Meyerhof–Parnas (EMP pathway), which was first discovered by Gustav Embden, Otto Meyerhof, and Jakub Karol Parnas.