He was a friend and associate of Cecil Rhodes (1853–1902), and was one of the three men who signed the original concession on which was based the British South Africa Company, of which he was president in 1923-25.
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The British South Africa Company was chartered the following October, and Maguire was associated with it for the rest of his life.
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In 1888, Rhodes sent him with Charles Rudd and Frank Thompson to negotiate a concession of land and mineral rights in Matabeleland from Chief Lobengula at Bulawayo.
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