Spottiswood, who was married before taking orders, left a son, Sir Henry Spottiswood, and a daughter Mary, who married Abraham Crichton; Abraham Creighton, 1st Baron Erne was their grandson.
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Through the Marquess of Buckingham, Spottiswood was appointed bishop of one of them, Clogher, based south-west Ulster, much of it in County Fermanagh.
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