After his death the Florida Herald published in seven parts Clarke's letter to Rev. Jedidiah Morse, D. D., corresponding secretary of the American Civilization Society.
Across New England, Reverend Jedidiah Morse and others sermonized against the Illuminati, their sermons were printed, and the matter followed in newspapers.
In 1805 he established The Panoplist for the purpose of illustrating and defending the commonly received orthodoxy of New England, and continued its sole editor for five years.
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He was very active in 1804 in the movement that resulted in enlarging the Massachusetts general assembly of Congregational ministers, and in 1805 unsuccessfully opposed, as a member of the board of overseers, the election of Henry Ware to the Hollis Chair of Divinity at Harvard.
As the top-ranked student, Ridge was asked to write an essay for President James Monroe, to be presented by Jedidiah Morse.
The Calvinist minister Jedidiah Morse published the chapter separately, as part of his campaign against New England's liberal ministers—contributing to "the Unitarian Controversy" (1815) that eventually produced permanent schism among New England's Congregationalist churches.
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Sprague wrote numerous books, including Lives of Rev. Edward Dorr Griffin, D. D, (1838), Timothy Dwight (1845), and Rev. Jedidiah Morse (1874), his greatest contribution to literature being his Annals of the American Pulpit, an invaluable compilation of Trinitarian Congregationalist, Presbyterian, Baptist, Methodist, Episcopalian, Unitarian Congregationalist, and other biographies.