He was the Democratic candidate in 2006 for Governor of Connecticut, unsuccessfully challenging incumbent Republican Governor M. Jodi Rell.
Following the completion of the Pfizer research facility in 2005, New Haven Mayor John DeStefano, Jr. and several leaders of local civic groups began pushing the Connecticut Department of Transportation to study removing the existing Oak Street Connector and replace it with a four-lane landscaped boulevard with access to local streets and businesses.
Cast bronze bas-relief plaques with profile portraits of Theodore Roosevelt by James Earle Fraser and of FDR by John DeStefano hung on the south wall until removal during a refurbishment during the second term of President George W. Bush.
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