During the 1850s, clinicians such as Armand Trousseau and John Hughlings Jackson held the prevailing view that the same linguistic deficiency occurred in writing as well as speech and reading impairments.
Ey developed an organodynamic psychology and a theory of the structure of states of consciousness, in which he developed ideas of Pierre Janet and John Hughlings Jackson.
After graduating in 1906 he worked at the National Hospital, Queen's Square (London) where he was influenced by brilliant neuroscientists such as Sir William Gowers, John Hughlings Jackson, Sir Victor Horsley and Sir Henry Head.
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After graduating with a B.A. from Harvard in 1878, Sachs travelled to Europe and studied under some of the more prominent physicians of the time, such as Adolf Kussmaul (1822–1902), Friedrich Daniel von Recklinghausen (1833–1910), Friedrich Goltz (1834–1902), Rudolf Virchow (1821–1902), Karl Friedrich Otto Westphal (1833–1890), Theodor Meynert (1833–1892), Jean-Martin Charcot (1825–1893), and John Hughlings Jackson (1835–1911).