On 18 May 2003 the Cathedral was re-consecrated by the Catholicos of All Armenians Karekin II and three other Armenian Apostolic bishops.
In 1999 he was elected Catholicos of All Armenians at the Mother See of Holy Etchmiadzin, succeeding Karekin I.
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His ecumenical trip to India to meet Baselios Thoma Didymos I, Catholicos of the East in November 2008, helped strengthen relations between the Armenian and Indian Orthodox Churches.
He was elevated to the rank of Archbishop in 2000 by His Holiness Karekin II, Catholicos of All Armenians.
Shoghakat TV company was founded in 1998 in Yerevan, Armenia, on the initiative of Catholicos Karekin II (at that time Archbishop Karekin Nersessian, Vicar General of the Araratian Pontifical Diocese of the Armenian Apostolic Church).
Gathered in the country's southern mountains near the border with Iran, guests including president Serzh Sarkisian and the head of the Armenian Apostolic Church, Karekin II, took part as the cable car link launched its first official voyage over the Vorotan River Gorge.