After studying at Japan Women's University and working at the office of Toyo Ito, in 1987, she founded Kazuyo Sejima and Associates.
Kazuyo Sejima and Ryue Nishizawa, partners of the Tokyo-based design firm SANAA, were selected as the lead architects in EPFL's international competition of December 2004.
Architects who previously worked for his office include Kazuyo Sejima and Ryue Nishizawa (SANAA), Astrid Klein and Mark Dytham (KDa), Katsuya Fukushima, Makoto Yokomizo, and Akihisa Hirata.