McGriff came to prominence in the early 1980s when he formed his own crack distributing organization which he called the Supreme Team based in the South Jamaica section of Queens, New York.
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In 2003, Kenneth "Supreme" McGriff, a convicted drug dealer and longtime friend of Murder Inc. heads Irv and Chris Gotti, was investigated for targeting Mizell because the DJ defied an industry blacklist of rapper 50 Cent that was imposed because of "Ghetto Qu'ran", a song 50 Cent wrote about McGriff's drug history.