Predation by feral tegus may pose a threat to Florida's endangered wildlife, such as the Key Largo woodrat and the American Crocodile.
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Four other Key Largo specialties: the Key Largo Woodrat, Key Largo Cotton Mouse, Schaus Swallowtail butterfly, Stock Island Treesnail are also listed as endangered, and the Eastern Indigo Snake is listed as threatened.
The Keys are also home to unique animal species, including the Key deer, protected by the National Key Deer Refuge, the American crocodile, and the Key Largo woodrat.