During the 2006 Texas gubernatorial election, the Burnt Orange Report published videos of a 1980 stand-up comedy performance by Kinky Friedman, in which he satirically used racial slurs.
Josh Alan has recorded and/or played with Sara Hickman, Keb' Mo', Kinky Friedman, Bugs Henderson, Phoebe Legere, and was a perennial opener in Texas for dozens of rock and blues acts, including Johnny Winter, Clarence "Gatemouth" Brown, War, Huey Lewis and the News, Bad Company, Mitch Ryder, Michael Nesmith and Wanda Jackson.
Kinky Friedman, an independent candidate, gained a good amount of popular support among Texas voters.
Milton Friedman | Thomas Friedman | Marty Friedman | Kinky Friedman | Marty Friedman (musician) | Peter Friedman | Lawrence M. Friedman | Glen E. Friedman | David F. Friedman | Stephen Friedman (PFIAB) | Rose Friedman | Menachem Friedman | Ken Friedman | Graeme Friedman | Friedman Memorial Airport | David D. Friedman | Bernard A. Friedman | William F. Friedman | Stephen J. Friedman | Roger Friedman | Ralph Friedman | Patri Friedman | Louis Friedman | Kinky Boots | Ignaz Friedman | Henryk Friedman | Friedman | Debbie Friedman | Dean Friedman | David Friedman |
National acts who have played Knuckleheads include Leon Russell, Nick Lowe, Edgar Winter and his brother Johnny Winter, Ray Price, Billy Joe Shaver, Dale Watson, Kinky Friedman, Rodney Crowell and David Lindley.
Notable past artists that have performed on "Local Live" to later gain greater recognition include The Black Keys, Spoon, ...And You Will Know Us by the Trail of Dead, Death Cab For Cutie, Ratatat, Shearwater, Kinky Friedman, Acid Mothers Temple, and Daniel Johnston.
Willie Nelson, Kinky Friedman, Roy Orbison, Delbert McClinton, Freddy Fender, Doug Sahm and Jerry Jeff Walker, were among Texas musicians who frequented the Lone Star Cafe.