Throughout most of its history the county was divided into fourteen hundreds, namely Bampton, Banbury, Binfield, Bloxham, Bullingdon, Chadlington, Dorchester, Ewelme, Langtree, Lewknor, Pyrton, Ploughley, Thame and Wootton.
He was knighted by Henry VI at Greenwich on 5 January 1453, alongside Edmund and Jasper Tudor, his brother Thomas, William Herbert, Roger Lewknor, and William Catesby.
Lewknor was one of Prince Henry's circle and contributed Old Wormy Age, a humorous panegyric verse, to the preface of Thomas Coryat's Coryat's Crudities: Hastily gobled up in Five Moneth’s Travels published in 1611.
Lewknor was the son of Christopher Lewknor, recorder of Chichester, and his wife Mary May, daughter of John May of Rawmere, Sussex.