After immigrating to the United States, he wrote a biography of his experiences with Mao entitled The Private Life of Chairman Mao.
In publicising The Private Life of Chairman Mao, Li Zhisui stated that he was Mao's personal physician for twenty-two years, in which time he became a close confidant of the Chinese leader, although this has since come under criticism from those who do not agree that Li's relationship was as close to Mao as he maintains.
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The Private Life of Chairman Mao: The Memoirs of Mao's Personal Physician is a memoir by Li Zhisui, one of the physicians to the former Chinese leader Mao Zedong, which was first published in 1994.