Following the capture of Robert de Ferrers, 6th Earl of Derby in 1266, following his rebellion against King Henry III, de Ferrers' lands and estates were confiscated; the associated from 1266 documents reveal there was a preceptory and leper hospital of the Order of St Lazarus at Locko, dedicated to St Mary Magdalene.
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In 1080, William de Ferrers, 3rd Earl of Derby granted the church of Spondon to the Leper Hospital and Brethren of St. Lazarus, at Burton Lazars in Leicestershire; This grant was later confirmed by both King Henry II and by King John.
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The site was moated and came with associated outbuildings, fishponds, and a spring (known as St Ann's Well).