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The landing stages at Lucerne and Flüelen provide 'cross-quay' interchange with the main line railways at Lucerne station and Flüelen station respectively.
From Olten the midland line connected to Bern and Thun, the Olten–Brugg line connected with the Swiss Northeastern Railway's (German: Schweizerische Nordostbahn, NOB) line to Zürich, the Jura foot line connected to Biel and the Olten–Lucerne railway line connected to Lucerne.