Khed lies off National Highway NH-17, popularly known as Mumbai-Goa Highway, that connects Khed with cities like Mangalore, Panaji, Madgaon, Karwar and Udupi.
Trains from here connect the city of Kollam to major cities of India, including New Delhi, Bangalore, Chennai, Indore, Bhopal, Hyderabad, Thiruvananthapuram, Mumbai, Madurai, Vizag, Jammu, Howrah, Guwahati, Madgaon, Hubli, Ahmedabad, Gwalior, Nagpur, Pune, Kota, Bhubaneshwar, Gorakhpur, Kochi, Kozhikode, Vijayawada, Bhubaneshwar, Coimbatore and Mangalore.
There are Maharashtra state government (MSRTC) buses running from Mumbai, Pune, Ratnagiri, Sangli, Kolhapur and Goa state government buses (Kadamba Transport Corporation) running from Panaji, Madgaon, Vasco and Pernem to Sindhudurg.
Kolhapur (Every 30 min from 6:00 to 19:00 and from 22:00 to 00:30), Panaji, Madgaon, Gadag, Karwar, Dharamshati, Chaandgadh, Deogadh, Sawantwadi, Ratnagiri, Malvan, Belgaum, Hubballi-Dharwad, Vengurla, Radhanagari, Kagal.