Their discovery represented the first example of an antimicrobial peptide produced in the skin of an animal, and complemented prior studies by Hans Boman of Sweden in the Cecropia moth, and Robert Lehrer (US) in rabbit white blood cells (defensins), supporting the widespread existence of antimicrobial peptides throughout nature.
He is known for his work on innate immunity and antimicrobial peptides including the discovery of Magainin from the frog Xenopus laevis.
Magainin |