The route runs northwest from Saco, passes very briefly through a Northwest corner of Biddeford, and intersects U.S. Route 202 near the Lyman-Waterboro line.
U.S. state | Georgia (U.S. state) | Maine | São Paulo (state) | Secretary of State | Washington (U.S. state) | state | United States Department of State | Moscow State University | United States Secretary of State | Ohio State University | Michigan State University | New York State Assembly | State Senator | New York State Senate | Rio de Janeiro (state) | Louisiana State Legislature | Iowa State University | Portland, Maine | Pennsylvania State University | Louisiana State University | Santa Catarina (state) | Florida State University | Paraná (state) | Vienna State Opera | Oregon State University | California State Assembly | Arizona State University | University at Buffalo, The State University of New York | Wayne State University |
Here converged three major Abenaki Indian paths—the Sokokis Trail (Route 5), the Ossipee Trail (Route 25) and the Pequawket Trail (Route 113), making it a central location for conducting with Native Americans the lucrative fur trade.
Here major Indian trails converged—the Sokokis Trail (now Route 5), the Ossipee Trail (now Route 25), and the Pequawket Trail (now Route 113) -- a location conducive towards lucrative fur trade with Indians, but also with risks of living isolated in the wilderness.