The Movie Die Hard with a Vengeance features John Mclane working for a fictionalized Major Case Unit
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The series Law & Order: Criminal Intent, depicts a fictionalized version of the NYPD Major Case Squad, one that investigates murders, which the real Major Case Squad does not do.
Major Case Squad (Major Crimes Unit), a division within some police departments
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Falacci is introduced in the episode "Seeds" as the temporary partner of Det. Mike Logan (Chris Noth), assigned to the Major Case Squad of the New York City Police Department (NYPD), due to Det. Megan Wheeler (Julianne Nicholson) going over to Europe to teach American police procedure to European police officers (covering Nicholson's first maternity leave).