In medicine, the mean circulatory filling pressure (Pmcf) is defined as the mean pressure that exists in the vascular system if the cardiac output stops and the pressure within the vascular system redistributes.
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It is an indicator of how full the circulatory system is (i.e. the volume of blood in the system compared to the capacity of the system), and is influenced by the volume of circulating blood and the smooth muscle tone in the walls of the venous system (which determines the capacity of the system).
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