Herb Melnick, a character from the television series Two and a Half Men, played by Ryan Stiles
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Don Melnick (contemporary), American environmental biologist and conservationist
Melnick became an independent producer, forming a company with David Susskind that produced the Emmy Award-winning TV productions aired on CBS, with Ages of Man starring John Gielgud in 1966, which included readings from William Shakespeare's works ranging from Romeo and Juliet to Richard II, with critic Jack Gould of The New York Times calling it "a viewing occasion to be treasured".