In humans however, Microcephaly is the only proven malformation, or congenital abnormality, found in the in Utero developing Human fetuses present during the Hiroshima and Nagasaki bombings.
PDE4DIP encodes a centrosomal protein and is a homolog of CDK5RAP2, a gene that lacks DUF1220 sequences and, when mutated, has been implicated in microcephaly.