She worked with him on expanding his first researches, around 1848, on the remarks previously made by Mitscherlich on the different optical properties concerning polarized light of tartaric acid when it came from natural wines, wine lees and when it was synthesized in a laboratory.
In that year Berzelius suggested Mitscherlich to the Prussian education minister Karl vom Stein zum Altenstein as successor to Martin Heinrich Klaproth at Berlin.