The majority of known data has been observed in the St. Joe and North Fork Clearwater River basins, but they also occur in the Selway, Kootenai, and Moyie drainages.
Another odd name occurring along the river is the town of Good Grief, Idaho.
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The river exits Moyie Lake to the south, flowing south and west by the village of Yahk, British Columbia and Yahk Provincial Park before entering Idaho at Kingsgate, British Columbia and Eastport, Idaho.
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Other than the Columbia and Kootenay Rivers, whose valleys form the bottomlands of the Rocky Mountain Trench, also included in the regional district are the northernmost parts of the basins of the Flathead, Moyie and Yahk Rivers (the Moyie and Yahk are tributaries of the Kootenay, entering it in the United States, and the Flathead is a tributary of the Clark Fork in Montana).