These compounds model biological complexes such as cytochrome P450, NO synthase, and isopenicillin N synthase.
Several mechanisms for nitrite conversion to NO have been described, including enzymatic reduction by xanthine oxidoreductase, nitrite reductase, and NO synthase (NOS), as well as nonenzymatic acidic disproportionation reactions.
These target genes encode proteins such as cyclooxygenase, NO synthase, phospholipase A2, tumor necrosis factor, transforming growth factor beta, ICAM-1, and a number of other pro-inflammatory proteins.
ATP synthase | NO synthase | ATP synthase subunit C | Salutaridine synthase | Ribbon diagram of Sucrose Synthase-1 3S27 Structure, isolated from ''Arabidopsis thaliana | Porphobilinogen synthase | Phosphoribosylaminoimidazolesuccinocarboxamide synthase |