She was the spouse of General Ignatius Kutu Acheampong, Chairman of the National Redemption Council and Supreme Military Council and Head of state of Ghana from 1972 to 1978.
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Under the National Redemption Council (NRC) and Supreme Military Council I (SMC I) governments led by General I.K. Acheampong, Odartey-Wellington served in various military command and civil administrative positions.