For Out, she visited a pathology autopsy class at a university but was not able to view a real corpse.
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She is most famous for her 1997 novel, Out, which received the Mystery Writers of Japan Award, Japan's top mystery award, and was a finalist (in English translation) for the 2004 Edgar Award.
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Kirino's works, such as Out, asks the reader what he/she would do if something awful happened to her/him.
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Many critics challenged and criticized Kirino for her storylines, especially for Out, by saying women should only be writing love stories.
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In addition to comparisons with hardboiled crime fiction, Kirino's work has been compared with horror fiction (the gruesome dismemberment scenes in Out, for example) and proletarian literature such as Kanikōsen.
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Auto (Tokyo: Kodansha, 1997); English translation by Stephen Snyder as Out (New York: Kodansha, 2003; New York: Vintage, 2005)