It is found only on Fernandina in the Galápagos Islands (part of Ecuador), which it shares with N. indefessus narboroughi.
Nesoryzomys indefessus narboroughi | Nesoryzomys darwini |
A smaller, related rice rat was also rediscovered—the Fernandina Rice Rat (Nesoryzomys fernandinae) on Fernandina.