The southern terminus of Route 12 was originally at New London, Connecticut.
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In the 1960s, the route was truncated and the northern terminus was moved to its present location at Morrisville, Vermont.
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New England Route 12 was a multi-state north–south state highway in the New England region of the United States, running from Groton, Connecticut, through Worcester, Massachusetts, and Keene, New Hampshire, to Morrisville, Vermont.
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